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1

ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload

Matsuo, Hirotaka, Nakayama, Akiyoshi, Sakiyama, Masayuki, Chiba, Toshinori, Shimizu, Seiko, Kawamura, Yusuke, Nakashima, Hiroshi, Nakamura, Takahiro, Takada, Yuzo, Oikawa, Yuji, Takada, Tappei, Nakaok

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

2

ABCG2 is a High-Capacity Urate Transporter and its Genetic Impairment Increases Serum Uric Acid Levels in Humans

Nakayama, Akiyoshi, Matsuo, Hirotaka, Takada, Tappei, Ichida, Kimiyoshi, Nakamura, Takahiro, Ikebuchi, Yuki, Ito, Kousei, Hosoya, Tatsuo, Kanai, Yoshikatsu, Suzuki, Hiroshi, Shinomiya, Nariyoshi

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2011

Language:

english

File:

PDF, 201 KB

english, 2011

3

ABCG2 Dysfunction Increases Serum Uric Acid by Decreased Intestinal Urate Excretion

Takada, Tappei, Ichida, Kimiyoshi, Matsuo, Hirotaka, Nakayama, Akiyoshi, Murakami, Keizo, Yamanashi, Yoshihide, Kasuga, Hiroshi, Shinomiya, Nariyoshi, Suzuki, Hiroshi

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2014

Language:

english

File:

PDF, 175 KB

english, 2014

4

Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2

Matsuo, Hirotaka, Tsunoda, Tomoyuki, Ooyama, Keiko, Sakiyama, Masayuki, Sogo, Tsuyoshi, Takada, Tappei, Nakashima, Akio, Nakayama, Akiyoshi, Kawaguchi, Makoto, Higashino, Toshihide, Wakai, Kenji, Ooya

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 448 KB

english, 2016

5

Two common PFIC2 mutations are associated with the impaired membrane trafficking of BSEP/ABCB11

Hisamitsu Hayashi, Tappei Takada, Hiroshi Suzuki, Hidetaka Akita, Yuichi Sugiyama

Journal:

Year:

2005

Language:

english

File:

PDF, 636 KB

english, 2005

6

Novel function of Niemann-Pick C1-like 1 as a negative regulator of Niemann-Pick C2 protein

Yoshihide Yamanashi, Tappei Takada, Jun-Ichi Shoda, Hiroshi Suzuki

Journal:

Year:

2012

Language:

english

File:

PDF, 1.66 MB

english, 2012

7

Molecular mechanisms of membrane transport of vitamin E

Tappei Takada, Hiroshi Suzuki

Journal:

Molecular Nutrition & Food Research

Year:

2010

Language:

english

File:

PDF, 281 KB

english, 2010

8

FIC1-mediated stimulation of FXR activity is decreased with PFIC1 mutations in HepG2 cells

Saori Koh, Tappei Takada, Ikuya Kukuu, Hiroshi Suzuki

Journal:

Journal of Gastroenterology

Year:

2009

Language:

english

File:

PDF, 456 KB

english, 2009

9

Characterization of Polarized Expression of Point- or Deletion-Mutated Human BCRP/ABCG2 in LLC-PK1 Cells

Tappei Takada, Hiroshi Suzuki, Yuichi Sugiyama

Journal:

Pharmaceutical Research

Year:

2005

Language:

english

File:

PDF, 780 KB

english, 2005

10

LXR Alpha Transactivates Mouse Organic Solute Transporter Alpha and Beta via IR-1 Elements Shared with FXR

Masae Okuwaki, Tappei Takada, Yuki Iwayanagi, Saori Koh, Yoshiaki Kariya, Hiroshi Fujii, Hiroshi Suzuki

Journal:

Pharmaceutical Research

Year:

2007

Language:

english

File:

PDF, 404 KB

english, 2007

11

HNF4α is a Crucial Modulator of the Cholesterol-Dependent Regulation of NPC1L1

Yuki Iwayanagi, Tappei Takada, Hiroshi Suzuki

Journal:

Pharmaceutical Research

Year:

2008

Language:

english

File:

PDF, 220 KB

english, 2008

12

Human NPC1L1 Expression is Positively Regulated by PPARα

Yuki Iwayanagi, Tappei Takada, Fumiya Tomura, Yoshihide Yamanashi, Tomohiro Terada, Ken-ichi Inui, Hiroshi Suzuki

Journal:

Pharmaceutical Research

Year:

2011

Language:

english

File:

PDF, 623 KB

english, 2011

13

Bafilomycin A1-sensitive pathway is required for the maturation of cystic fibrosis transmembrane conductance regulator

Tsukasa Okiyoneda, Akiko Niibori, Kazutsune Harada, Taijun Kohno, Yasuaki Hashimoto, Hiroyuki Kusuhara, Tappei Takada, Tsuyoshi Shuto, Mary Ann Suico, Yuichi Sugiyama, Hirofumi Kai

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2006

Language:

english

File:

PDF, 487 KB

english, 2006

14

Characterization of 5′-Flanking Region of Human MRP3

Tappei Takada, Hiroshi Suzuki, Yuichi Sugiyama

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 136 KB

english, 2000

15

Transport by vesicles of glycine- and taurine-conjugated bile salts and taurolithocholate 3-sulfate: A comparison of human BSEP with rat Bsep

Hisamitsu Hayashi, Tappei Takada, Hiroshi Suzuki, Reiko Onuki, Alan F. Hofmann, Yuichi Sugiyama

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2005

Language:

english

File:

PDF, 427 KB

english, 2005

16

Calreticulin facilitates the cell surface expression of ABCG5/G8

Tsukasa Okiyoneda, Taijun Kono, Akiko Niibori, Kazutsune Harada, Hiroyuki Kusuhara, Tappei Takada, Tsuyoshi Shuto, Mary Ann Suico, Yuichi Sugiyama, Hirofumi Kai

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 277 KB

english, 2006

17

Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4

Yuki Ikebuchi, Tappei Takada, Kousei Ito, Takashi Yoshikado, Naohiko Anzai, Yoshikatsu Kanai, Hiroshi Suzuki

Journal:

Hepatology Research

Year:

2009

Language:

english

File:

PDF, 605 KB

english, 2009

18

Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis

Masanori Ito, Yoshihide Yamanashi, Yu Toyoda, Hiroko Izumi-Nakaseko, Satoko Oda, Atsushi Sugiyama, Masaru Kuroda, Hiroshi Suzuki, Tappei Takada, Satomi Adachi-Akahane

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

19

Ursodeoxycholic acid stimulates the formation of the bile canalicular network

Yuki Ikebuchi, Hidetoshi Shimizu, Kousei Ito, Takashi Yoshikado, Yoshihide Yamanashi, Tappei Takada, Hiroshi Suzuki

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.18 MB

english, 2012

20

NPC2 Regulates Biliary Cholesterol Secretion via Stimulation of ABCG5/G8-Mediated Cholesterol Transport

Yoshihide Yamanashi, Tappei Takada, Takashi Yoshikado, Jun–Ichi Shoda, Hiroshi Suzuki

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 2.22 MB

english, 2011

21

Molecular identification of species and ploidy ofCarassiusfishes in Lake Biwa, using mtDNA and microsatellite multiplex PCRs

Mishina, Tappei, Takada, Mikumi, Takeshima, Hirohiko, Nakano, Mitsunori, Tabata, Ryoichi, Nishida, Mutsumi, Watanabe, Katsutoshi

Journal:

Ichthyological Research

Year:

2014

Language:

english

File:

PDF, 345 KB

english, 2014

22

A common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility

Sakiyama, Masayuki, Matsuo, Hirotaka, Shimizu, Seiko, Chiba, Toshinori, Nakayama, Akiyoshi, Takada, Yuzo, Nakamura, Takahiro, Takada, Tappei, Morita, Emi, Naito, Mariko, Wakai, Kenji, Inoue, Hiroki, T

Journal:

Year:

2014

Language:

english

File:

PDF, 210 KB

english, 2014

23

Erratum to: Molecular identification of species and ploidy ofCarassiusfishes in Lake Biwa, using mtDNA and microsatellite multiplex PCRs

Mishina, Tappei, Takada, Mikumi, Takeshima, Hirohiko, Nakano, Mitsunori, Tabata, Ryoichi, Nishida, Mutsumi, Watanabe, Katsutoshi

Journal:

Ichthyological Research

Year:

2014

Language:

english

File:

PDF, 180 KB

english, 2014

24

Decreased extra-renal urate excretion is a common cause of hyperuricemia

Ichida, Kimiyoshi, Matsuo, Hirotaka, Takada, Tappei, Nakayama, Akiyoshi, Murakami, Keizo, Shimizu, Toru, Yamanashi, Yoshihide, Kasuga, Hiroshi, Nakashima, Hiroshi, Nakamura, Takahiro, Takada, Yuzo, Ka

Journal:

Nature Communications

Year:

2012

Language:

english

File:

PDF, 418 KB

english, 2012

25

Organic Cation Transporter/Solute Carrier Family 22a is Involved in Drug Transfer into Milk in Mice

Ito, Naoki, Ito, Kousei, Ikebuchi, Yuki, Kito, Tomoko, Miyata, Hiroshi, Toyoda, Yu, Takada, Tappei, Hisaka, Akihiro, Honma, Masashi, Oka, Akira, Kusuhara, Hiroyuki, Suzuki, Hiroshi

Journal:

Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 491 KB

english, 2014

26

NPT1/SLC17A1 Is a Renal Urate Exporter in Humans and Its Common Gain-of-Function Variant Decreases the Risk of Renal Underexcretion Gout

Chiba, Toshinori, Matsuo, Hirotaka, Kawamura, Yusuke, Nagamori, Shushi, Nishiyama, Takashi, Wei, Ling, Nakayama, Akiyoshi, Nakamura, Takahiro, Sakiyama, Masayuki, Takada, Tappei, Taketani, Yutaka, Sum

Journal:

Arthritis & Rheumatology

Year:

2015

Language:

english

File:

PDF, 1.91 MB

english, 2015

27

ABCG2 Dysfunction Increases the Risk of Renal Overload Hyperuricemia

Matsuo, Hirotaka, Takada, Tappei, Nakayama, Akiyoshi, Shimizu, Toru, Sakiyama, Masayuki, Shimizu, Seiko, Chiba, Toshinori, Nakashima, Hiroshi, Nakamura, Takahiro, Takada, Yuzo, Sakurai, Yutaka, Hosoya

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2014

Language:

english

File:

PDF, 302 KB

english, 2014

28

Prediction of Drug Transfer into Milk Considering Breast Cancer Resistance Protein (BCRP)-Mediated Transport

Ito, Naoki, Ito, Kousei, Ikebuchi, Yuki, Toyoda, Yu, Takada, Tappei, Hisaka, Akihiro, Oka, Akira, Suzuki, Hiroshi

Journal:

Pharmaceutical Research

Year:

2015

Language:

english

File:

PDF, 422 KB

english, 2015

29

ABCG2/BCRP Dysfunction as a Major Cause of Gout

Matsuo, Hirotaka, Takada, Tappei, Ichida, Kimiyoshi, Nakamura, Takahiro, Nakayama, Akiyoshi, Suzuki, Hiroshi, Hosoya, Tatsuo, Shinomiya, Nariyoshi

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2011

Language:

english

File:

PDF, 391 KB

english, 2011

30

A Common Variant of Organic Anion Transporter 4 (OAT4/SLC22A11) Gene Is Associated with Renal Underexcretion Type Gout

Sakiyama, Masayuki, Matsuo, Hirotaka, Shimizu, Seiko, Nakashima, Hiroshi, Nakayama, Akiyoshi, Chiba, Toshinori, Naito, Mariko, Takada, Tappei, Suzuki, Hiroshi, Hamajima, Nobuyuki, Ichida, Kimiyoshi, S

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 116 KB

english, 2014

31

Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors

Nakayama, Akiyoshi, Matsuo, Hirotaka, Nakaoka, Hirofumi, Nakamura, Takahiro, Nakashima, Hiroshi, Takada, Yuzo, Oikawa, Yuji, Takada, Tappei, Sakiyama, Masayuki, Shimizu, Seiko, Kawamura, Yusuke, Chiba

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 351 KB

english, 2014

32

Ethnic Differences in ATP-binding Cassette Transporter, Sub-family G, Member 2 (ABCG2/BCRP): Genotype Combinations and Estimated Functions

Sakiyama, Masayuki, Matsuo, Hirotaka, Takada, Yuzo, Nakamura, Takahiro, Nakayama, Akiyoshi, Takada, Tappei, Kitajiri, Shin-ichiro, Wakai, Kenji, Suzuki, Hiroshi, Shinomiya, Nariyoshi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2014

Language:

english

File:

PDF, 117 KB

english, 2014

33

Functional analysis of nonsynonymous single nucleotide polymorphism type ATP-binding cassette transmembrane transporter subfamily C member 3

Kobayashi, Kazuhiro, Ito, Kousei, Takada, Tappei, Sugiyama, Yuichi, Suzuki, Hiroshi

Journal:

Pharmacogenetics and Genomics

Year:

2008

Language:

english

File:

PDF, 363 KB

english, 2008

34

In-vitro characterization of the six clustered variants of NPC1L1 observed in cholesterol low absorbers

Yamanashi, Yoshihide, Takada, Tappei, Suzuki, Hiroshi

Journal:

Pharmacogenetics and Genomics

Year:

2009

Language:

english

File:

PDF, 373 KB

english, 2009

35

Common variant of PDZ domain containing 1 (PDZK1) gene is associated with gout susceptibility: A replication study and meta-analysis in Japanese population

Higashino, Toshihide, Matsuo, Hirotaka, Sakiyama, Masayuki, Nakayama, Akiyoshi, Nakamura, Takahiro, Takada, Tappei, Ogata, Hiraku, Kawamura, Yusuke, Kawaguchi, Makoto, Naito, Mariko, Kawai, Sayo, Taka

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2016

Language:

english

File:

PDF, 257 KB

english, 2016

36

Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter

Suzuki, Shingo, Shuto, Tsuyoshi, Sato, Takashi, Kaneko, Masayuki, Takada, Tappei, Suico, Mary Ann, Cyr, Douglas M., Suzuki, Hiroshi, Kai, Hirofumi

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 3.29 MB

english, 2014

37

Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals

Furukawa, Junji, Inoue, Katsuhisa, Maeda, Junya, Yasujima, Tomoya, Ohta, Kinya, Kanai, Yoshikatsu, Takada, Tappei, Matsuo, Hirotaka, Yuasa, Hiroaki

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

38

Transporter-mediated Regulation of Pharmacokinetics of Lifestyle-related Substances

Journal:

YAKUGAKU ZASSHI

Year:

2013

File:

PDF, 816 KB

2013

39

Transportsome in biliary cholesterol secretion

Takada, Tappei, Yamanashi, Yoshihide, Suzuki, Hiroshi

Journal:

Folia Pharmacologica Japonica

Year:

2012

File:

PDF, 799 KB

2012

40

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes

Nakayama, Akiyoshi, Nakaoka, Hirofumi, Yamamoto, Ken, Sakiyama, Masayuki, Shaukat, Amara, Toyoda, Yu, Okada, Yukinori, Kamatani, Yoichiro, Nakamura, Takahiro, Takada, Tappei, Inoue, Katsuhisa, Yasujim

Journal:

Annals of the Rheumatic Diseases

Year:

2017

Language:

english

File:

PDF, 1.13 MB

english, 2017

41

Halogenated hydrocarbon solvent-related cholangiocarcinoma risk: biliary excretion of glutathione conjugates of 1,2-dichloropropane evidenced by untargeted metabolomics analysis

Toyoda, Yu, Takada, Tappei, Suzuki, Hiroshi

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.82 MB

english, 2016

42

Common dysfunctional variants in ABCG2 are a major cause of early-onset gout

Matsuo, Hirotaka, Ichida, Kimiyoshi, Takada, Tappei, Nakayama, Akiyoshi, Nakashima, Hiroshi, Nakamura, Takahiro, Kawamura, Yusuke, Takada, Yuzo, Yamamoto, Ken, Inoue, Hiroki, Oikawa, Yuji, Naito, Mari

Journal:

Scientific Reports

Year:

2013

Language:

english

File:

PDF, 321 KB

english, 2013

43

Immunohistochemical and in situ hybridization study of urate transporters GLUT9/URATv1, ABCG2, and URAT1 in the murine brain

Naoko H. Tomioka,Yoshifuru Tamura,Tappei Takada…

Journal:

Fluids and Barriers of the CNS

Year:

2016

Language:

english

File:

PDF, 1.88 MB

english, 2016

44

VLDL/LDL acts as a drug carrier and regulates the transport and metabolism of drugs in the body

Yamamoto, Hideaki, Takada, Tappei, Yamanashi, Yoshihide, Ogura, Masatsune, Masuo, Yusuke, Harada-Shiba, Mariko, Suzuki, Hiroshi

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.18 MB

english, 2017

45

Erratum: Corrigendum: Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals

Furukawa, Junji, Inoue, Katsuhisa, Maeda, Junya, Yasujima, Tomoya, Ohta, Kinya, Kanai, Yoshikatsu, Takada, Tappei, Matsuo, Hirotaka, Yuasa, Hiroaki

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 120 KB

english, 2016

46

Effect of luteolin on the expression of intestinal cholesterol transporters

Ogawa, Mana, Yamanashi, Yoshihide, Takada, Tappei, Abe, Keiko, Kobayashi, Shoko

Journal:

Journal of Functional Foods

Year:

2017

Language:

english

File:

PDF, 670 KB

english, 2017

47

Multiple common and rare variants of ABCG2 cause gout

Higashino, Toshihide, Takada, Tappei, Nakaoka, Hirofumi, Toyoda, Yu, Stiburkova, Blanka, Miyata, Hiroshi, Ikebuchi, Yuki, Nakashima, Hiroshi, Shimizu, Seiko, Kawaguchi, Makoto, Sakiyama, Masayuki, Nak

Journal:

Year:

2017

Language:

english

File:

PDF, 689 KB

english, 2017

48

Investigation of the transport of xanthine dehydrogenase inhibitors by the urate transporter ABCG2

Nakamura, Makiko, Fujita, Kyoko, Toyoda, Yu, Takada, Tappei, Hasegawa, Hiroshi, Ichida, Kimiyoshi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2017

Language:

english

File:

PDF, 401 KB

english, 2017

49

Transporters for the Intestinal Absorption of Cholesterol, Vitamin E, and Vitamin K

Yamanashi, Yoshihide, Takada, Tappei, Kurauchi, Ryoya, Tanaka, Yusuke, Komine, Toko, Suzuki, Hiroshi

Journal:

Journal of Atherosclerosis and Thrombosis

Year:

2017

Language:

english

File:

PDF, 3.46 MB

english, 2017

50

Spontaneous Production of Glutathione-Conjugated Forms of 1,2-Dichloropropane: Comparative Study on Metabolic Activation Processes of Dihaloalkanes Associated with Occupational Cholangiocarcinoma

Toyoda, Yu, Takada, Tappei, Suzuki, Hiroshi

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2017

Language:

english

File:

PDF, 1.89 MB

english, 2017

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